Dr.Carole Franske Homeopath Canada
Meera Shanglo Homeopathic Research Centre India There are two differient clinical trail on two groups of 50 patients each. One group of trail is for Insulin dependant diabetic patients and the other group if of normal diabetic patients. In insulin dependant diabetic patients. The patients who were taking insulin more than three times a day are there. With the help of your medicnine and constitutional homeopathic treatment it has been reduced to once a day or once every alternate day.In diabetic foot also the amputation is averted in 4 cases and in most of the cases the medicine is given to the patient who were on the verge of amputation and the they are responding good. The other group is the normal diabetic patients who are taking your medicne along with any other allopathic or homeopathic medicnes. In those patients also the the dosage of allopathic medicnes has reduced and their quality of life which is acesssed by general weakness, libido,numbness of extremities and heat of palms and soles tingling sensatin etc. Insulin-like Growth Factor - IGF1 As a widely effective hormone/ growth factor/ neuropeptide, IGF-1, generally exerts its effects on growth and healing, especially in the liver, muscles, intestines and in the nervous, immune, and hormonal systems. IGF-1 regulates which cells progress into DNA synthesis. IGF-1 exerts its regulatory effects as a cell-signaling molecule without the necessity of entering the cell through activation of specific, high affinity, cell-surface receptors. Insulin-like Growth FactorInsulin-like Growth Factor-1 (IGF1) is released by many different tissues throughout the body and affects almost every cell to some degree. Major organs that synthesize IGF1 are the human placenta, heart, lung, kidney, liver, pancreas, spleen, small intestines, testes, ovaries, large intestines, brain, bone and pituitary. Humans produce approximately 10 milligrams of IGF1 per day until about 30 years old whereby production decreases with aging. IGF1 has similarities to insulin and possesses potent anabolic and cell growth effects. IGF1 is also important for its affect on development, diabetes and other chronic diseases. IGF1 is primarily secreted by the liver in response to a signal from human growth hormone (hGH). The major target tissues affected by the IGF1 in combination with the hGH signal are muscle, cartilage, bone, liver, kidney, nerves, skin and lungs. IGF1 is known as a 'progression' factor. IGF1 assists competent cells toward cell division and often that is all cells need for successful activation. IGF1 cooperates with PDGF to increase the cell's ability to complete DNA synthesis. IGF1 not only helps cell growth by division, but also by enhancing cell specialization. Hormonal functions such as the anabolic (constructive) activity of hGH depends on the production and presence of IGF1 to achieve positive results. - IGF1 increases physical performance, mental performance, and physical endurance in healthy individuals.
- IGF1 communicates an anabolic signal to cells, regulating cell division and differentiation as the muscle acquires an increased need for strength or as injury to the muscle is incurred.
- IGF1 promotes the growth of muscle and bone.
- IGF1 acts within the nervous system and is critical for the growth and development of nerve cells.
- IGF1 maintains a high level of cell communication at the neuromuscular junction, where the cooperation between the nerve and muscle cells take place.
IGF2 (Insulin-like Growth Factor 2) Benefits Pinchas Cohen, M.D. The IGFs are important metabolic and mitogenic factors involved in cell growth and metabolism. IGFs are produced in the liver, in bone cells, and in other tissues, at least partially under GH control. Circulating IGFs have direct (endocrine) effects on somatic growth and on the proliferation of many tissues and cell types, both in vivo and in vitro. However, the IGFs are also thought to be significant autocrine-paracrine factors involved in cellular proliferation. Locally produced IGFs have been demonstrated in bone, brain, prostate, muscle, mammary tissue, and other sites, where they are considered to be responsible for tissue growth and differentiation. About 80 percent of serum IGF-I levels are hepatic in origin as evident from specific liver targeting of IGF-I.[7] |